The Rip Van Wrinkler, XVII, Issue 4, November 2013
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SOME HEALTH & SCIENCE NEWS |
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Blood Typing A good reason for blood-typing has to do with the possibility of fading puppy syndrome. This is similar to the human Rh factor incompatibility, when the Mother is Rh negative and Father is Rh positive. If you breed a dog with one blood type to a bitch with another, the first time you do it, everything will be okay. If you repeat the breeding, or breed this bitch to another dog with the same blood type as the first mate, however, the bitch previously sensitized by the first mating will develop antibodies to that sire's blood, and puppies carrying the blood type of the sire can die, once they suckle the dam's colostrum, which is carrying these anti-sire's blood type antibodies. Canine neonatal isoerythrolysis (NI): 1) May occur if a DEA 1.1 negative bitch who has been previously sensitized to DEA 1.1 positive cells by a mismatched blood transfusion is bred to a DEA 1.1 positive male dog, and she produces DEA 1.1 positive pups. (DEA 1.1 positive bitches are not at risk for producing pups that develop neonatal isoerythrolysis) 2) Dog placenta does not allow for passive transfer of antibody (ie - anti-DEA antibody) during pregnancy. DEA 1.1 positive puppies are exposed to DEA 1.1 antibody through colostrum ingestion 3) Pups are normal at birth and develop hemolytic anemia in 3-10 days. |
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